Location: US-45 and Route 145, Massac Cty Reassurance shield after Route 145. Location: US-45 and I-24, Massac Cty Just after 145, we’ll approach Interstate 24. Location: US-45 and I-24, Massac Cty Turn right for I-24 west. Stay straight for 24 east. Location: US-45 and I-24, Massac Cty Follow I-24 west to Interstate 57. Odd choice … Continue reading U.S. Route 45, IL-145 to I-24